Yes, just be sure you understand your niche and that you try only to attract clients who are comfortable working with you on a virtual basis. My firm is virtual, and I have operated as a digital nomad to various degrees. Still, for centuries, people have used accountants either in the office down the hall or who have an office within a 15-minute drive. You will inevitably attract a client or two in a particular geographic location, and they will not understand when you are no longer physically close by.

Other important factors are that you have the necessary technology and are comfortable using it. At a minimum:

Secure Online file sharing
Electronic signature options
Online accounting software